Preheat oven to 400 F, option to line a baking sheet with parchment paper for easy clean up.
Pat tilapia completely dry and place in a 9 x 13 casserole dish. Sprinkle filets with salt, pepper, and smoked paprika, and press to adhere.
In a small bowl, whisk together the lemon juice, melted butter, and garlic. Pour over the tilapia.
Bake in preheated oven until the tilapia is white all the way through, and flakes easily, about 12-14 minutes. Garnish with parsley before serving, and enjoy!